Researchers Use Stem Cells to Grow Functioning Kidney Tissue Inside the Human Body

Medical Marvel

In a remarkable medical first, research funded by The Medical Research Council and Kidney Research U.K. helped researchers create human kidney tissue inside of a living organism. The tissue was even capable of producing urine. This amazing achievement could one day yield novel treatments for kidney disease.

To do this, the research team, led by Professors Sue Kimber and Adrian Woolf from the University of Manchester, started with human embryonic stem cells grown in a culture broth specifically designed for kidney development. They turned these cells into microscopic kidney pieces.

Building a mini-kidney. Image Credit: University of Manchester
Building a mini-kidney. Image Credit: University of Manchester

These pieces were combined with a gel that worked as connective tissue. This mixture was then injected under the skin of mice. Thanks to careful design, three months later the researchers found something, well,  incredible.

The substance had developed into microscopic structural and functional kidney units known as nephrons. Most of the parts found in human nephrons were present in the experimental mice. These parts worked together to filter blood and excrete a detectable amount urine, which the researchers confirmed with a fluorescent stain. This study is published in the journal Stem Cell Reports.

Mini-Kidneys

While these “mini-kidneys,” are lacking a vital artery that would allow them to function on their own, “We have proved beyond any doubt these structures function as kidney cells by filtering blood and producing urine — though we can’t yet say what percentage of function exists,” Kimber said in a press release.

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This is only a proof-of-principle study, so it simply represents a first step that will be followed up by much more research and exploration. Woolf explained in the press release that “we must now turn to developing an exit route for the urine and a way to deliver this technology to diseased kidneys.”

Sill, with further development, this kidney tissue technique could one day replace or improve existing tools for treating kidney disease. Such a medical advancement could improve and even lengthen the lives of millions.

“Worldwide, 2 million people are being treated with dialysis or transplantation for kidney failure, and sadly another 2 million die each year, unable to access these treatments,” Woolf noted in the press release. “So we are tremendously excited by this discovery — we feel it is a big research milestone which may one day help patients.”

The post Researchers Use Stem Cells to Grow Functioning Kidney Tissue Inside the Human Body appeared first on Futurism.

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Kantar calls iPhone X pricing ‘vindicated’ as Apple sees marketshare grow across Europe, China, Australia & Japan

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As hand wringing over the $ 999-and-up pricing of the iPhone X continues, analysts at Kantar Worldpanel see the premium-priced handset as a wise move for Apple, after tracking marketshare gains for iOS in a number of key markets across the globe.
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TEGNA to Grow OTT Ad Network Through Investment in Tubi TV

TEGNA Inc. today announced a strategic investment in Tubi TV, the industry’s leading free streaming and TV movie network.

The investment extends TEGNA’s position in the over-the-top (OTT) space and builds on its leadership in offering marketers access to local advertising in long-form OTT content.

Premion, the company’s first-of-its-kind local ad network for OTT content, will expand its existing relationship with Tubi TV to better serve advertising clients.

Tubi TV has the largest premium library of entertainment content with more than 7,500 movies and TV series available per month, as well as a proprietary content personalization engine and onboarding process to create a customized viewing experience. Tubi TV will distribute TEGNA’s local content across its platform, offering viewers localized news and other digital content from TEGNA stations.

Tubi TV has also seen success with their leading advertising technology platform, which combines data targeting with a robust analytics platform. In addition to adding Tubi TV to a roster of premium OTT providers, Premion will also be able to better serve local and national advertisers through user-targeted, differentiated ads.

“Tubi TV strongly aligns with TEGNA’s focus on OTT content and innovative advertising solutions,” said Dave Lougee, president and CEO, TEGNA. “Through this transaction, we continue to fuel Premion’s growth trajectory and will enhance their ability to deliver unique and high-performing ads in a way no one else can.”

The post TEGNA to Grow OTT Ad Network Through Investment in Tubi TV appeared first on Mobile Marketing Watch.


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Tactical Monsters Rumble Arena: How to grow your monster squad fast

It’s not glamorous work wrangling monsters in Tactical Monsters Rumble Arena, at least to start. The game features legendary creatures like Dracula and Medusa, but they aren’t on your roster when you begin playing, and you could find yourself decidedly underwhelmed by your early game choices.

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Why crowdfunding will grow in 2018


Odds are you’ve been asked to contribute to a new product or cause via Kickstarter, GoFundMe, Indiegogo, or another crowdfunding site at some point or another in the last few years. Although popular crowdfunding sites like those only launched as early as 2008, the fact is, you’ve been participating in crowdfunding for a long time. You just didn’t know it. Crowdfunding is defined as “the practice of funding a project or venture by raising many small amounts of money from a large number of people, typically via the Internet,” says Wikipedia. By that definition, every time you bought wrapping paper…

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