Localization is a vital, but less talked-about part of the technology industry — and it can lead to a lucrative career, too. Now, to help people enter the field, Google just launched a free course on the Udacity online learning platform called Localization Essentials. This six-lesson series is fronted by two Google localization professionals, and features interviews, guides and quizzes, and represents a gentle introduction to the localization field. It introduces you to the challenges localization engineers face on a daily basis, as well as the tools they use. The course also gives you a hint of what you can expect…
Clickers can be fun not just because of the passivity, being a great way to pass time when doing something else or if you’re feeling particularly brain dead. But also, they can scratch the itch of building something up to impressive heights…only to tear it down and start all over again. In fact, that idea of restarting has become a key part of many clickers, to a point where you could almost speedrun a clicker – one of our readers has talked about how he has speedruns through Bit City [Free], for example. But a clicker that’s centered around speedruns? That seems like an interesting idea. That could be what Power Tap does.
See, Power Tap is an idle clicker about generating power for ever-more power-hungry devices. You’ll tap to generate power, and use various items and enhancements to increase your power generation. But, the game has a finite ending after 60 levels, and about 8 hours of time spent in the game. Now, when you win, you get super-bonuses that allow you to start off with a head start next time. This sounds like other clickers, but instead, you can make your way back through even faster. I could see some real potential for the game as a speedrun title, with possible Game Center leaderboards for fastest time through. Or, if you just want a clicker you can beat, and put down without ever getting to that “I’m tired of this” point, a la Spaceplan [$ 2.99], Power Tap could be the clicker for you. Check out the forum thread to chat about this one ahead of its expected release in June.
An experiment involving dermatological health, an immune cell, and a shaved mouse may have just accidentally led to a new theory about hair loss. Michael Rosenblum, assistant professor of dermatology at the University of California, San Francisco, has discovered that regulatory T cells (tregs) serve a much more important function in recovery than we previously believed.
Scientists thought that the cells only served an immune function, informing other cells what to attack. Rosenblum made the discovery when he removed the tregs from an area of a mouse to see the effect it had on the skin — but when he shaved the mouse to observe the effects of his experiment he realized the hair didn’t grow back.
When the team researched more they discovered that tregs in the skin — as opposed to their usual location in lymph nodes — contain unusually high levels of Jagged 1 (Jag1), which is responsible for calling in the stem cells. This is called ‘notch signaling’. When these tregs were removed, notch signaling was severely reduced, and when they added microscopic beads covered in Jag1, restoring the notch signaling chain, stem cells were called which successfully activated follicle regeneration.
So. Much. Hair.
As this discovery is at the intersection of hair loss and the immune system, it is particularly good news for one type of hair loss sufferer in particular: individuals with alopecia areata (an autoimmune disease that impedes hair follicle regeneration). Alopecia is one of the most common autoimmune deficiencies in humans: it impacts 1.7 percent of the population in the U.S, which amounts to 4.6 Million people. Until now, scientists have had little idea of what causes hair loss as a symptom, but this discovery gives doctors and scientists a causal explanation and a potential cure.
The effects of the discovery, though, extend beyond hair regeneration: it also makes us more aware of the recovery process of other skin-related damage, such as wound repair. While, traditionally, the model has been that immune cells fight infection while stem cells repair damage, Rosenblum told The Telegraph “what we found here is that stem cells and immune cells have to work together to make regeneration possible.”
Our hair is, obviously, very important to us. It can represent our style, our heritage, even our profession. Hair loss can be unbelievably devastating, altering self esteem and identity: therefore it is extremely important that research like this — and recent discoveries in enzyme therapy and Sea Anemone proteins — continue.
It's hard to believe it's been almost three years since Amazon announced its plan to deliver packages via drone. The first air delivery occurred last December in the UK and the retailer continues to refine the concept with futuristic ideas to perch t… Engadget RSS Feed